Safety

1. Identification Of The Substance/Mixture And Of The Company Undertaking

Product Name	Methanol
Product Code(s)	3-34-2600-2
UN-Number	UN1230
Synonyms	MeOH
Recommended Use	Formalin, Acetic acid, Methyl Methacrylate, Methyl chlorides, Coating compounds, Synthetic resins, Solvent, Pharmaceutical.
Emergency Telephone Number	+81-25-259-3111
E-mail Address	-
Registration Number	No information available.

2. Hazards Identificaion

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GHS-Classification
Acute Oral Toxicity	Category 3
Acute Dermal Toxicity	Category 3
Acute Inhalation Toxicity - Dusts and Mists	Category 3
Reproductive Toxicity	Category 2
Specific Target Organ Systemic Toxicity (Single Exposure)	Category 1
GHS Label elements, including precautionary statements
Signal Word	Danger
Hazard Statements	Toxic if swallowed Toxic in contact with skin Toxic if inhaled Suspected of damaging fertility or the unborn child Causes damage to organs
Physical Hazards	Flammable liquids
Physical Hazard Statements	Highly flammable liquid and vapor
Precautionary Statements	Prevention Obtain special instructions before use Do not handle until all safety precautions have been read and understood Use personal protective equipment as required Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Do not breathe dust/ fume/ gas/ mist/ vapors/ spray Use only outdoors or in a well-ventilated area Avoid release to the environment Keep away from heat/ sparks/ open flames/ hot surfaces. - No smoking Keep container tightly closed Ground/bond container and receiving equipment Use explosion-proof electrical/ ventilating/ lighting/ equipment Use only non-sparking tools Take precautionary measures against static discharge Keep cool General Advice Specific treatment (see supplemental first aid instructions on this label) Specific measures (see supplemental first aid instructions on this label) IF exposed: Call a POISON CENTER or doctor/physician Specific treatment (see supplemental instructions on the administration of antidotes on this label) Skin Specific treatment (see supplemental first aid instructions on this label) Specific measures (see supplemental first aid instructions on this label) IF exposed: Call a POISON CENTER or doctor/physician Specific treatment (see supplemental instructions on the administration of antidotes on this label) Inhalation IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing Call a POISON CENTER or doctor/physician Ingestion IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician Rinse mouth Fire In case of fire: Use CO2, dry chemical, or foam for extinction Storage Store locked up Store in a well-ventilated place. Keep container tightly closed Disposal Dispose of contents/container to an approved waste disposal plant
Other information	May cause eye, skin, and respiratory tract irritation Inhalation, ingestion, or skin absorbtion of methanol can cause blindness

3. Composition/Information on Ingredients

Synonyms	MeOH
Hazardous Ingredients	Chemical Name: Methyl alcohol CAS-No: 67-56-1 Weight %: 99.9 EC-No: 200-659-6

4. First Aid Measures

General Advice	Immediate medical attention is required. Show this safety data sheet to the doctor in attendance.
Hazardous Ingredients	mmediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
Skin Contact	Wash off immediately with plenty of water. Get medical attention immediately if symptoms occur.
Inhalation	Immediate medical attention is required. Move to fresh air. If not breathing, give artificial respiration. Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation.
Ingestion	Do NOT induce vomiting. Call a physician or Poison Control Center immediately. Never give anything by mouth to an unconscious person. Drink plenty of water.
Notes to Physician	Early administration of ethanol may counter the toxic effects (metabolic acidosis, renal damage). Consult standard literature for details of treatment. 4-Methyl pyrazole (Antizol®) is an effective blocker of alcohol dehydrogenase and should be used in the treatment of ethylene glycol (EG), di- or triethylene glycol (DEG, TEG), ethylene glycol butyl ether (EGBE), or methanol intoxication if available. Fomepizole prevents renal injury. The long elimination half-life of methanol poisonings, with absent hemodialysis, necessitates prolonged administration of fomepizole. Fomepizole may also obviate the need for hemodialysis in selected methanol-poisoned patients, in the absence of neurological and ocular impairment or severe acidosis if adminstreprotocol. The signs and symptoms of poisoning include metabolic acidosis, CNS depression, renal tubular injury, and possible late stage cranial nerve involvement. Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure should be observed 24-48 hours for signs of respiratory distress. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.
Protection of First-aiders	Remove all sources of ignition.

5. Fire Fighting Measures

Flammable Properties	HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Suitable Extinguishing Media	Carbon dioxide (CO2). Alcohol-resistant foam. Dry chemical. Water spray.
Unsuitable Extinguishing Media	No information available.
Specific Hazards Arising from the Chemical	Keep product and empty container away from heat and sources of ignition.
Protective Equipment and Precautions for Firefighters	Wear self-contained breathing apparatus and protective suit.

6. Accidental Release Measures

Personal Precautions	Remove all sources of ignition. Evacuate personnel to safe areas. Ensure adequate ventilation.
Environmental Precautions	Prevent further leakage or spillage if safe to do so. Prevent product from entering drains.
Methods for Containment	Prevent further leakage or spillage if safe to do so. Dike far ahead of liquid spill for later disposal.
Methods for Cleaning Up	Dam up. Soak up with inert absorbent material. Pick up and transfer to properly labeled containers.
Other Information	Not applicable.

7. Handling And Storage

Handling	Ensure adequate ventilation. Keep away from open flames, hot surfaces and sources of ignition. Take precautionary measures against static discharges. Use only in an area containing flame proof equipment. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.
Storage	Keep tightly closed in a dry and cool place. Keep in properly labeled containers.
Incompatible Products	Oxidizing agents.

8. Exposure Controls/Personal Protection

Exposure Guidelines	Chemical Name	Methyl Alcohol
	Japan	TWA: 200 ppm TWA: 260 mg/m3 Skin
	China	TWA: 25 mg/m3 STEL: 50 mg/m3 Skin
	Hong Kong	TWA: 200 ppm TWA: 262 mg/m3 STEL: 250 ppm STEL: 328 mg/m3
	Indonesia	NAB: 200 ppm NAB: 262 mg/m3 Skin
	Malaysia	TWA: 200 ppm TWA: 262 mg/m3 Skin
	Philippines	TWA: 200 ppm TWA: 260 mg/m3
	Singapore	STEL: 250 ppm STEL: 328 mg/m3 PEL: 200 ppm PEL: 262 mg/m3
	Korea	Skin STEL: 250 ppm STEL: 310 mg/m3 TWA: 200 ppm TWA: 260 mg/m3
	Taiwan	TWA: 200 ppm TWA: 262 mg/m3
	Thailand
Engineering Measures	Ensure adequate ventilation, especially in confined areas.
Personal Protective Equipment	Eye/Face Protection Tightly fitting safety goggles. Skin and Body Protection Antistatic boots. Wear fire/flame resistant/retardant clothing. Impervious gloves. Respiratory Protection When workers are facing concentrations above the exposure limit they must use appropriate certified respirators. In case of insufficient ventilation wear suitable respiratory equipment.
Hygiene Measures	When using, do not eat, drink or smoke. Provide regular cleaning of equipment, work area and clothing.

9. Physical And Chemical Properties

Physical State	Liquid
Appearance	Clear
Odor	Irritating
Odor Threshold	No information available
pH	No data available
Melting Point/Range	-96°C
Freezing Point	No information available
Initial Boiling Point	No information available
Boiling Point/Boiling Range	64.65°C
Flash Point	11°C
Evaporation Rate	No data available
Flammable Properties	HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Explosive Properties	No information available
Oxidizing Properties	No information available
Vapor Pressure	No data available
Vapor Density	No data available
Specific Gravity	0.7928
Water Solubility	Soluble in water.
Solubility	Soluble
Partition Coefficient: n-octanol/water	No data available
Autoignition Temperature	No data available
Decomposition Temperature °C	No information available
Viscosity	0.59 cP @ 20°C

10. Stability And Reactivity

Stability	Stable under normal conditions.
Conditions to Avoid	Heat, flames and sparks.
Incompatible Products	Oxidizing agents.
Hazardous Decomposition Products	None under normal use.
Hazardous Reactions	None under normal processing.
Hazardous Polymerization	None under normal processing.

11. Toxicological Information

Product Information
Acute Toxicity	Methanol is readily absorbed by inhalation, ingestion and dermal exposure, and it is rapidly distributed to tissues. Methanol is metabolized primarily in the liver to formaldehyde, formic acid and carbon dioxide. Humans and non-human primates are uniquely sensitive to the toxic effects of methanol. It is the rate of metabolic detoxification (or removal of formate) that is vastly different between rodents and primates and is the basis for the dramatic differences in methanol toxicity observed between rodents and primates. As a result, fatal methanol poisoning occurs as a result of metabolic acidosis and neuronal toxicity. Toxic effects are characterized by formic acidemia, metabolic acidosis, ocular toxicity, nervous system depression, blindness, coma and death. Although ingestion dominates as the most frequent route of poisoning, inhalation of high concentrations of methanol vapor and percutaneous absorption of methanolic liquids are as effective as the oral route in producing acute toxic effects..
	Chemical Name : Methyl alcohol LD50 Oral : 5628 mg/kg ( Rat ) LD50 Dermal : 15800 mg/kg ( Rabbit ) LC50 Inhalation : 83.2 mg/L ( Rat ) 4 h | 64000 ppm ( Rat ) 4 h
Chronic Toxicity
Carcinogenicity	Did not show carcinogenic effects in animal experiments.
Irritation	Eye, rabbit: Moderately irritating to the eyes.
Corrosivity	No information available.
Sensitization	Did not cause sensitization on laboratory animals.
Neurological Effects	Methanol has been shown to cause central nervous system depression, ocular toxicity, and blindness.
Mutagenic Effects	Negative in multiple in vitro and in vivo assays.
Reproductive Toxicity	No information available.
Developmental Toxicity	May be a developmental hazard based on animal data.
Target Organ Effects	Eyes. Central nervous system (CNS). Gastrointestinal tract (GI). Respiratory system. Liver. Kidney. Cardiovascular system
Other Adverse Effects	Long-term exposure to lower levels of methanol has been shown to cause a broad range of ocular effects, including blurring, constriction of the visible field, changes in color perception, and temporary or permanent blindness. Overexposure to methanol may result in visual disturbances, nausea, abdominal and muscle pain, dizziness, weakness and disturbances of consciousness ranging from coma to clonic seizures.

12. Ecological Information

Ecotoxicity
0 % of the mixture consists of component(s) of unknown hazards to the aquatic environment
Chemical Name	Methyl alcohol
Toxicity to Algae	-
Toxicity to Fish	LC50 96 h: 13500 - 17600 mg/L flow-through (Lepomis macrochirus) LC50 96 h: 18 - 20 mL/L static (Oncorhynchus mykiss) LC50 96 h: 19500 - 20700 mg/L flow-through (Oncorhynchus mykiss) LC50 96 h: = 28200 mg/L flow-through (Pimephales promelas) LC50 96 h: > 100 mg/L static (Pimephales promelas)
Toxicity to Microorganisms	EC50 = 39000 mg/L 25 min EC50 = 40000 mg/L 15 min EC50 = 43000 mg/L 5 min
Daphnia Magna (Water Flea)	-
Persistence and Degradability	No information available.
Bioaccumulation	No information available.
Mobility	No information available.
Chemical Name	Methyl alcohol
Log Pow	-0.77

13. Disposal Considerations

Waste from Residues / Unused Products	Dispose of in accordance with local regulations.
Contaminated Packaging	Empty containers should be taken to an approved waste handling site for recycling or disposal.

14. Transport Information

IMDG/IMO	Proper Shipping Name	Methanol
	Hazard Class	3
	Subsidiary Class	6.1
	UN-Number	UN1230
	Packing Group	II
	EmS No.	F-E, S-D
ICAO	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Subsidiary Class	6.1
	Packing Group	II
IATA	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Subsidiary Class	6.1
	Packing Group	II
DOT	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Subsidiary Class	6.1
	Packing Group	II
TDG	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Subsidiary Class	(6.1)
	Packing Group	II
MEX	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Subsidiary Class	6.1
	Packing Group	II
RID	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Classification Code	FT1
	Packing Group	II
ADR	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Classification Code	FT1
	Packing Group	II
HI No.	336
ADN	UN-Number	UN1230
	Proper shipping name	Methanol
	Hazard Class	3
	Classification Code	FT1
	Packing Group	II
	Special Provisions	279, 802

15. Regulatory Informations

International Inventories	All of the components in the product are on the following Inventory lists: U.S.A. (TSCA), Canada (DSL/NDSL), Europe (EINECS/ELINCS/NLP), Australia (AICS), Korea (ECL), China (IECSC), Japan (ENCS), Philippines (PICCS).
TSCA	Complies
EINECS/ELINCS	Complies
DSL/NDSL	Complies
PICCS	Complies
ENCS	Complies
IECSC	Complies
AICS	Complies
KECL	Complies
Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory EINECS/ELINCS - European Inventory of Existing Commercial Chemical Substances/EU List of Notified Chemical Substances DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List PICCS - Philippines Inventory of Chemicals and Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances AICS - Australian Inventory of Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances
RESTRICTIONS - REACH TITLE VIII	No information available.

16. Other Information

Prepared By	Product Stewardship 23 British American Blvd. Latham, NY 12110 1-800-572-6501
Issuing Date	26-Apr-2011
Revision Date
Revision Note	Initial Release.
Recommended Restrictions	No information available.
General Disclaimer The information provided on this MSDS is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text.